Hoag Hospital in Newport Beach is now enrolling patients in a clinical trial to study an innovative surgical procedure that would allow surgeons to repair a patient’s mitral valve without open-heart surgery.

The RESTORE clinical trial, in collaboration with Edwards Lifesciences, will evaluate the safety and effectiveness of the investigational HARPOON Beating Heart Mitral Valve Repair System for patients with severe degenerative mitral valve regurgitation, a condition commonly caused by mitral valve prolapse, which prevents the valve from closing properly and causes blood to leak backwards into the lungs causing shortness of breath.